New Study Reveals COVID-19’s Impact on Coronary Arteries, Increasing Cardiovascular Risk
A groundbreaking study funded by the National Heart, Lung, and Blood Institute (NHLBI) and other institutes of the National Institutes of Health (NIH) has shed light on the direct impact of the SARS-CoV-2 virus on coronary arteries. The research reveals that the virus can infect the arteries and cause inflammation in fatty plaque, significantly increasing the risk of heart attack and stroke.
The study primarily focused on older individuals with underlying atherosclerotic plaque who tragically passed away due to COVID-19. However, the implications of the findings extend to anyone who contracts the virus, urging a heightened awareness of the potential cardiovascular complications.
While previous research has indicated the ability of SARS-CoV-2 to infect tissues like the brain and lungs, less was known about its impact on the coronary arteries. The latest study found that the virus has a higher rate of infecting macrophages in the arteries, specifically cholesterol-laden foam cells. This suggests that foam cells may act as reservoirs for the virus in plaque.
Another significant observation made by the researchers was the release of cytokines, molecules known for increasing inflammation and promoting the formation of more plaque, after infecting the plaque with the virus. These findings help explain why individuals with preexisting plaque buildup who contract COVID-19 may experience cardiovascular complications even after recovering from the infection.
It is important to note that the study’s conclusions are specific to the original strains of SARS-CoV-2 circulating in New York City between May 2020 and May 2021. Therefore, the results may not be generalized to younger, healthier individuals or to different strains of the virus.
The NIH, including the NHLBI, is dedicated to advancing medical research and understanding diseases affecting the heart, lungs, and blood. As a global leader in this field, the NIH continues its tireless efforts to uncover vital information to protect individuals from the severe consequences of COVID-19.
The findings of this study highlight the significance of ongoing research into the effects of the virus on various bodily systems. By better understanding the relationship between SARS-CoV-2 and the cardiovascular system, medical professionals can develop targeted interventions to mitigate the heightened risks for vulnerable individuals.
As we navigate the pandemic, the study serves as a stark reminder of the importance of following public health guidelines, especially for those with preexisting conditions. By staying informed and prioritizing our health, we can collectively work towards reducing the impact of COVID-19 on cardiovascular health.
